T&A cloning publications

T&A cloning


1. The lolB gene in Xanthomonas campestris pv. campestris is required for bacterial attachment, stress tolerance, and virulence. Liao, CT., Li, CE., Chang, HC. et al.BMC Microbiol, 2022

 2. First report of acanthocephalan parasite, Longicollum pagrosomi Yamaguti, 1935 in cultured red snapper (Lutjanus erythropterus) in Taiwan. Cheng, L. W., Rao, S., Wang, P. C., & Chen, S. C. – Journal of Fish Diseases, 2022

3. Interrelationship of Gut Microbiota, Obesity, Body Composition and Insulin Resistance in Asians with Type 2 Diabetes Mellitus. Pai, C. S., Wang, C. Y., Hung, W. W., Hung, W. C., Tsai, H. J., Chang, C. C., … & Tsai, Y. C. – Journal of Personalized Medicine, 2022

4. The suppressive role of phytochemical-induced glutathione S-transferase Mu 2 in human urothelial carcinoma cells. Shen, C. H., Wu, J. Y., Wang, S. C., Wang, C. H., Hong, C. T., Liu, P. Y., … & Liu, Y. W. – Biomedicine & Pharmacotherapy, 2022

5. H101G Mutation in Rat Lens αB-Crystallin Alters Chaperone Activity and Divalent Metal Ion Binding. Wu, Y. Y., Desu, N. K., Lu, S. Y., Yu, B. Y., Kumar, R., & Huang, F. Y. – Current Pharmaceutical Biotechnology, 2022


1. DEVELOPMENT OF A UPL PROBE-BASED REAL-TIME PCR ASSAY OF PORCINE DELTACORONAVIRUS IN TAIWAN. Chao-Nan Lin, Ming-Tang Chiou, Fu-Chun Hsueh, Wei-Hao Lin, Chuen-Fu Lin, Cheng-Yao Yang and Shara Png Si Wei – Taiwan Veterinary Journal, 2021

2. Quercetin blocks the aggressive phenotype of triple-negative breast cancer by inhibiting IGF1/IGF1R-mediated EMT program. Chen WJ, Tsai JH, Hsu LS, Lin CL, Hong HM, Pan MH. – J Food Drug Anal., 2021

3. Circulating androgen regulation by androgen-catabolizing gut bacteria in male mouse gut. Tsun-Hsien Hsiao, Chia-Hong Chou, Yi-Lung Chen, Po-Hsiang Wang, Guo-Jie Brandon-Mong, Tzong-Huei Lee, Tien-Yu Wu, Po-Ting Li, Chen-Wei Li, Yi-Li Lai, Yu-Lin Tseng, Chao-Jen Shih, Mei-Jou Chen, Yin-Ru Chiang – bioRxiv, 2022

4. Whole-cell biocatalyst of recombinant tyrosine ammonia lyase with fusion protein and integrative chaperone in Escherichia coli for high-level p-Coumaric acid. Sefli Sri Wahyu Effendi, Chengfeng Xue, Shih-I Tan, I-Son Ng – Journal of the Taiwan Institute of Chemical Engineers, 2021

5. A novel C-type lectin LvCTL 4.2 has antibacterial activity but facilitates WSSV infection in shrimp (L. vannamei). Yu-Hsun Huang, Ramya Kumar, Chun-Hung Liu, Shih-Shun Lin, Han-Ching Wang – Developmental & Comparative Immunology, 2022

6. Rapid detection of plum pox virus by reverse transcription recombinase polymerase amplification. Jeong, HW., Lee, HJ., Cho, IS. et al.Journal of Plant Diseases and Protection, 2021

7.  Incidence and Effects of Acquisition of the Phage-Encoded ssaSuperantigen Gene in Invasive Group A Streptococcus. Chiang-Ni C, Liu YS, Lin CY, Hsu CY, Shi YA, Chen YM, Lai CH, Chiu CH – Front Microbiol., 2021

8. Ultrarapid Inflammation of the Olfactory Bulb After Spinal Cord Injury: Protective Effects of the Granulocyte Colony-Stimulating Factor on Early Neurodegeneration in the Brain. Lin MS, Chiu IH, Lin CC. – Front Aging Neurosci., 2021

9. Enhancing the Insecticidal Potential of Baculovirus by Overexpressing the Mammalian Β-Galactosyl Binding Protein Galectin-1. Lin, C. Y., Lin, Y. C., Wu, Y., & Huang, R. N. – Taiwan Veterinary Journal, 2021

10. Gut Microbiota and Subclinical Cardiovascular Disease in Patients with Type 2 Diabetes Mellitus. Tsai, H. J., Tsai, W. C., Hung, W. C., Hung, W. W., Chang, C. C., Dai, C. Y., & Tsai, Y. C. – Nutrients, 2021

11. Down-regulation of A Human Herpesvirus 1 (HHV-1) MicroRNA in Infected Cells by Goniothalamin Treatment. Yip, C. W., Nor, N. S. M., & Ibrahim, N. –bioRxiv, 2021

12. In Litopenaeus vannamei, the cuticular chitin-binding proteins LvDD9A and LvDD9B retard AHPND pathogenesis but facilitate WSSV infection. Chen, Y. L., Kumar, R., Liu, C. H., & Wang, H. C. – Developmental & Comparative Immunology, 2021

13. Genotype and virulence gene analyses of Bacillus cereus group clinical isolates from the Chinese softshell turtle (Pelodiscus sinensis) in Taiwan. Cheng, L. W., Rao, S., Poudyal, S., Wang, P. C., & Chen, S. C. – Journal of Fish Diseases, 2021

14. Clinical implications of serum hepatitis B virus pregenomic RNA kinetics in chronic hepatitis B patients receiving antiviral treatment and those achieving HBsAg loss. Wu, I. C., Liu, W. C., Chiu, Y. C., Chiu, H. C., Cheng, P. N., & Chang, T. T. – Microorganisms, 2021

15. The Association of Targeted Gut Microbiota with Body Composition in Type 2 Diabetes Mellitus. Hung, W. C., Hung, W. W., Tsai, H. J., Chang, C. C., Chiu, Y. W., Hwang, S. J., … & Tsai, Y. C. – International journal of medical sciences, 2021

16. Efficient and economical targeted insertion in plant genomes via protoplast regeneration. Hsu, C. T., Yuan, Y. H., Lin, Y. C., Lin, S., Cheng, Q. W., Wu, F. H., … & Lin, C. S. –The CRISPR Journal, 2021

17. Gemcitabine-induced Gli-dependent activation of hedgehog pathway resists to the treatment of urothelial carcinoma cells. Chang, Y. H., Tam, H. L., Lu, M. C., & Huang, H. S. – PloS one, 2021

18. Production of High Amylose and Resistant Starch Rice Through Targeted Mutagenesis of Starch Branching Enzyme Iib by Crispr/cas9. Wang, H. C., Hsu, Y. C., Wu, Y. P., Yeh, S. Y., & Ku, M. S. – Research Square, 2021

19. Análisis del perfil de metilación CpG del ADN genómico de una población con incongruencia de género. Ramirez Olivero, K. D. V. – Universidade da Coruña. Facultade de Ciencias, 2021


1.AKT1 internal tandem duplications and point mutations are the genetic hallmarks of sclerosing pneumocytoma. Yi-Chen Yeh , Hsiang-Ling Ho, Yu-Chung Wu, Chin-Chen Pan, Yu-Chao Wang ,Teh-Ying Chou –Modern Pathology ,2020

2.DEAD-Box RNA Helicase 42 Plays a Critical Role in Pre-mRNA Splicing under Cold Stress. Chung-An Lu, Chun-Kai Huang, Wen-Shan Huang, Tian-Sheng Huang, Hsin-Yi Liu, and Yu-Fu Chen- Plant Physiology,2020

3.Induction of Robust Immune Responses by CpGODN-Loaded Hollow Polymeric Nanoparticles for Antiviral and Vaccine Applications in Chickens. Shu-Yi Lin, Bing-Yu Yao,Che-Ming Jack Hu, Hui-Wen Chen- International Journal of Nanomedicine,2020

4.Metformin Mitigates Nickel-Elicited Angiopoietin-Like Protein 4 Expression via HIF-1α for Lung Tumorigenesis, Yu-Ting Kang, Wen-Cheng Hsu, Chu-Chyn Ou, Hui-Chun Tai, Hui-Ting Hsu, Kun-Tu Yeh, Jiunn-Liang Ko- International Journal of Molecular Sciences,2020

5.Human cytomegalovirus pp65 peptide-induced autoantibodies cross-reacts with TAF9 protein and induces lupus-like autoimmunity in BALB/c mice. Ao-Ho Hsieh, Chang-Fu Kuo, I-Jun Chou, Wen-YiTseng, Yen-FuChen, KuangHuiYu & Shue-Fen Luo- Scientific Reports,2020

6.Enzymatic Cleavage of 3’-Esterifed Nucleotides Enables a Long, Continuous DNA Synthesis. Shiuan-Woei LinWu, Ting-YuehTsai , Yu-HsuanTu, Hung-WenChi , Yu-PingTsao, YaChenChen, Hsiang-MingWang, Wei-HsinChang, Chung-FanChiou, Johnsee Lee & ChengYao Chen- Scientific Reports,2020

7.Caspase dependent apoptosis is required for anterior regeneration in Aeolosoma viride and its related gene expressions are regulated by the Wnt signaling pathway, Sheridan Ke-Wing Fok, Chiao-Ping Chen, Tzu-Lun Tseng, Yi-Hua Chiang, Jiun-Hong Chen- Scientific Reports,2020

8.PCR Detection and Phylogenetic Analysis of Megalocytivirus Isolates in Farmed Giant Sea Perch Lates calcarifer in Southern Taiwan, Jia-Ming Tsai, Song-Lang Huang, Chung-Da Yang-Viruses ,2020

9.Gender-Affirming Hormone Therapy Modifies the CpG Methylation Pattern of the ESR1 Gene Promoter After Six Months of Treatment in Transmen. Rosa Fernández, PhD, Karla Ramírez, Esther Gómez-Gil, MD, Joselyn Cortés-Cortés, PhD, Mireia Mora, MD, Gloria Aranda, MD, Enrique Delgado Zayas, Isabel Esteva, MD, Mari Cruz Almaraz, MD, Antonio Guillamon, MD, and Eduardo Pásaro, PhD- The Journal of Sexual Medicine,2020


1.Strategies at Bioreactor Scale for the Production of Recombinant Proteins in Yarrowia lipolytica, Marie Vandermies, Patrick Fickers- Microorganisms,2019

2.The Characteristics and Expression Profile of Transferrin in the Accessory Nidamental Gland of the Bigfin Reef Squid during Bacteria Transmission, Hau-Wen Li, Chih Chen, Wei-Lun Kuo, Chien-Ju Lin, Ching-Fong Chang, Guan-Chung Wu- Scientific Reports,2019

3.Rapid analysis of bacterial composition in prosthetic joint infection by 16S rRNA metagenomic sequencing, Mei-Feng Chen, Chih-Hsiang Chang, Chuan Chiang-Ni, Pang-Hsin Hsieh, Hsin-Nung Shih, Steve W. N. Ueng, Yuhan Chang-Bone & Joint,2019


1.Functional characterization of the gene promoter for an Elaeis guineensis phosphate tarvation-inducible, high affinity phosphate transporter in both homologous and heterologous model systems, Farzaneh Ahmadi- Plant Physiology and Biochemistry,2018

2.Satellite DNA in Paphiopedilum subgenus Parvisepalum as revealed by highthroughput sequencing and fluorescent in situ hybridization. Yung-I Lee, Jing Wei Yap, Shairul Izan, Ilia J. Leitch, Michael F. Fay, Yi-Ching Lee , Oriane Hidalgo , Steven Dodsworth, Marinus J. M. Smulders , Barbara Gravendeeland Andrew R. Leitch-BMC Genomics,2018

3.Telomere maintenance during anterior regeneration and aging in the freshwater annelid Aeolosoma viride. chi-Fan Chen, Tzu-Ling Sung, Liuh-Yow Chen & Jiun-Hong Chen Scientific Reports,2018

4.Phosphorylated OmpR Is Required for Type 3 Fimbriae Expression in Klebsiella pneumoniae Under Hypertonic Conditions, Tien-Huang Lin1, Yeh Chen, Jong-Tar Kuo, Yi-Chyi Lai, Chien-Chen Wu, Chun-Fa Huang, Ching-Ting Lin- Front Microbiol,2018

5.A novel role of ER stress signal transducer ATF6 in regulating enterovirus A71 viral protein stability. Jia-Rong Jheng1 , Kean-Seng Lau1 , Yueh-Wen Lan1 and Jim-Tong Horng- Journal of Biomedical Science,2018

6.Genetic and Epigenetic Perturbations by DNMT3A-R882 Mutants Impaired Apoptosis through Augmentation of PRDX2 in Myeloid Leukemia Cells. Rabindranath Bera , Ming-Chun Chiu , Ying-Jung Huang , Der-Cherng Liang , Yun-Shien Lee and Lee-Yung Shih-Neoplasia,2018


  1. Cloning of phaCAB genes from thermophilic Caldimonas manganoxidans in Escherichia coli for poly (3-hydroxybutyrate)(PHB) production. JH Lin, MC Lee, YS Sue, YC Liu, SY Li – Applied Microbiology and Biotechnology, 2017

2.Identification and expression analysis of two pro-inflammatory cytokines, TNF-α and IL-8, in cobia (Rachycentron canadum L.) in response to Streptococcus dysgalactiae infection. TTT Nguyen, HT Nguyen, PC Wang- Fish & Shellfish Immunology, 2017

3.Generation of Aptamers from A Primer-Free Randomized ssDNA Library Using Magnetic-Assisted Rapid Aptamer Selection. Shih-Ming Tsao, Ji-Ching Lai, Horng-Er Horng, Tu-Chen Liu & Chin-Yih Hong-Scientific Reports,2017

4.Phylodynamic and Genetic Diversity of Canine Parvovirus Type 2c in Taiwan.Yung-Cheng Lin, Shu-Yun Chiang, Hung-Yi Wu, Jih-Hui Lin, Ming-Tang Chiou, Hsin-Fu Liu, Chao-Nan Lin-Molecular Sciences,2017

5.Detection and Diversity of the Nitrite Oxidoreductase Alpha Subunit (nxrA) Gene of Nitrospina in Marine Sediments.Sundas Rani, Hyeon-Woo Koh, Sung-Keun Rhee, Hirotsugu Fujitani & Soo-Je Park.Microbial Ecology,2017

6.Identification and expression analysis of two pro-inflammatory cytokines, TNF-a and IL-8, in cobia (Rachycentron canadum L.) in response to Streptococcus dysgalactiae infection. Thuy Thi Thu Nguyen , Hai Trong Nguyen, Pei-Chyi Wang , Shih-Chu Chen- Fish & Shellfish Immunology,2017

7.Cloning of phaCAB genes from thermophilic Caldimonas manganoxidans in Escherichia coli for poly(3-hydroxybutyrate) (PHB) production. Ji-Hong Lin& Ming-Chieh Lee & You-Sheng Sue & Yung-Chuan Liu & Si-Yu Li- Applied Microbiology and Biotechnology,2017

8.Two MYB-related transcription factors play opposite roles in sugar signaling in Arabidopsis, Yi-Shih Chen, Yi-Chi Chao, Tzu-Wei Tseng, Chun-Kai Huang, Pei-Ching Lo, Chung-An Lu- Plant Molecular Biology,2017


1.Functional characterization and transcriptome analysis reveal multiple roles for prc in the pathogenicity of the black rot pathogen Xanthomonas campestris pv. CT Liao, YF Liu, YC Chiang, HH Lo, SC Du…,PC Hsu,YM Hsiao- Research in Microbiology, 2016

2.Global Transcriptome Analysis of Gracilaria changii (Rhodophyta) in Response to Agarolytic Enzyme and Bacterium. EL Lim, RS Siow, RA Rahim, CL Ho – Marine biotechnology, 2016

3.A new rapid and efficient system with dominant selection developed to inactivate and conditionally express genes in Candida albicans. WC Lai, HFS Sun, PH Lin, H Lin, JC Shieh – Current genetics, 2016

4.A novel paramyxean parasite, Marteilia octospora n. sp.(Cercozoa) infecting the Grooved Razor Shell clam Solen marginatus from Galicia (NW Spain). M Ruiz, C López, RS Lee, R Rodríguez .,SusanaDarriba,- Journal of invertebrate Pathology, 2016

5.Host microRNA miR-197 plays a negative regulatory role in the enterovirus 71 infectious cycle by targeting the RAN protein. WF Tang, RT Huang, KY Chien, JY Huang, Kean-Seng Laua, Jia-Rong Jhenga, Cheng-Hsun Chiub, Tzong-Yuan Wuc, Chung-Yung Chenc and Jim-Tong Hornga, – Journal of virology, 2016

6.The infectious bronchitis vaccine strain virus is more pathogenic in chicken embryos than the wild virus strain. CT Tsai, HY Chiou, CH Wang – Veterinarski arhiv, 2016

7.Comparative genetic analyses of human rhinovirus C (HRV-C) complete genome from Malaysia. YS Khaw, YF Chan, FL Jafar, N Othmanm, Hui Yee Chee – Frontiers in microbiology,2016

8.Aligning to the sample-specific reference sequence to optimize the accuracy of next-generation sequencing analysis for hepatitis B virus. WC Liu, CP Lin, CP Cheng, CH Ho, KL Lan – Hepatology International, 2016

9.Crayfish plague Aphanomyces astaci detected in redclaw crayfish, Cherax quadricarinatus in Taiwan. CY Hsieh, CW Huang, YC Pan – Journal of invertebrate pathology, 2016

10.Seasonal changes in bacterial communities associated with healthy and diseased Porites coral in southern Taiwan. CH Lin, CH Chuang, WH Twan ,Shu-Fen Chiou,e Tit-Yee Wong,f Jong-Kang Liu,g Chyuan-yao Kao,b Jimmy Kuobc,- Canadian journal of Microbiology, 2016

11.Characterization of genes encoding proteins containing HD-related output domain in Xanthomonas campestris pv. Campestris. HM Lee, CT Liao, YC Chiang, YY Chang, Yu-Tzu, YehShin,Chiao DuYi,Min Hsiao , Antonie van Leeuwenhoek, 2016

12.A Novel Metallo-β-Lactamase Involved in the Ampicillin Resistance of Streptococcus pneumoniae ATCC 49136 Strain. CY Chang, HJ Lin, BR Li, YK Li – PloS one, 2016

13.Synaptotagmin-like protein 2 gene promotes the metastatic potential in ovarian cancer. HY Sung, J Han, W Ju, JH Ahn – Oncology reports, 2016

14.Surveillance and Evaluation of the Infection Risk of Free-Living Amoebae–Acanthamoeba in Aquatic Environments. BM Hsu – International Journal of Environmental Science and technology, 2016

15.Two highly similar DEAD box proteins, OsRH2 and OsRH34, homologous to eukaryotic initiation factor 4AIII, play roles of the exon junction complex in regulating growth and development in rice. H Chun-Kai, YS Sie, C Yu-Fu, H Tian-Sheng Tian-Sheng, Huang; Chung-An, Lu- BMC Plant Biology , 2016

16.Oil Palm Defensin: A Thermal Stable Peptide that Restricts the Mycelial Growth of Ganoderma boninense. YC Tan, CL Ang, MY Wong, CL Ho – Protein and peptide letters, 2016

17.DNA barcoding reveals that the common cupped oyster in Taiwan is the Portuguese oyster Crassostrea angulata (Ostreoida; Ostreidae), not C. gigas. ST Hsiao, SC Chuang, KS Chen, PH Ho, CL Wu – Scientific reports,

18.DDX3 functions in antiviral innate immunity through translational control of PACT. MC Lai, HS Sun, SW Wang, WY Tarn – The FEBS journal, 2016

19.Characterization of mussel H2A. Z. 2: a new H2A. Z variant preferentially expressed in germinal tissues from Mytilus. C Rivera-Casas, R Gonzalez-Romero, Ángel Vizoso-Vazquez,Manjinder S. Cheema,c M. Esperanza Cerdán,b Josefina Méndez,d Juan Ausió,c Jose M. Eirin-Lopeza- Biochemistry and Cell Biology, 2016

20.Both Phosphorus Fertilizers and Indigenous Bacteria Enhance Arsenic Release into Groundwater in Arsenic-Contaminated Aquifers. TY Lin, CC Wei, CW Huang, CH Chang, – Journal of agricultural , 2016

21.Distinct function of metal-reducing bacteria from sediment and groundwater in controlling the arsenic mobilization in sedimentary aquifer. KL Lu, CW Liu, VHC Liao, CM Liao – J Bioremed Biodeg, 2016 – gwater.agec.ntu.edu.tw

22.Seasonal difference of human adenoviruses in a subtropical river basin based on 1-year monthly survey. CW Tao, BM Hsu, PM Kao, WC Huang, TK Hsu, Ying-Ning HoYen-Ju LuCheng-Wei Fan- Environmental Science and Pollution Research, 2016

23.Characterisation of fosfomycin resistance mechanisms and molecular epidemiology in extended-spectrum β-lactamase-producing Klebsiella pneumoniae isolates. PL Lu, YJ Hsieh, JE Lin, JW Huang, TY Yang,LLin,ST Tseng – International journal of Antimicrobial ,2016

24.Oil Palm Defensin: A Thermal Stable Peptide that Restricts the Mycelial Growth of Ganoderma boninense. YC Tan, CL Ang, MY Wong, CL Ho – Protein and peptide letters, 2016

25.Positive regulation of HIF-1A expression by EBV oncoprotein LMP1 in nasopharyngeal carcinoma cells. WW Sung, YC Chu, PR Chen, MH Liao, JW Lee – Cancer letters, 2016

26.An l-ascorbate-6-phosphate lactonase from Streptococcus pneumoniae ATCC 49136 strain reveals metallo-β-lactamase activity. CY Chang, BR Li, YK Li – International journal of antimicrobial agents, 2016

27.Open and closed evolutionary paths for drastic morphological changes, involving serial gene duplication, sub-functionalization, and selection. G Abe, SH Lee, J Li, CJ Chang, K Tamura, KG Ota – Scientific reports, 2016


1.PecS regulates the urate-responsive expression of type 1 fimbriae in Klebsiella pneumoniae CG43. ZC Wang, CJ Liu, YJ Huang, YS Wang , HLing Peng- Microbiology,2015

2.Functional properties of the major outer membrane protein in Stenotrophomonas maltophilia. YY Chen, HC Wu, JW Lin, SF Weng – Journal of Microbiology, 2015

3.Gene expression profiling of fatty acid biosynthetic pathway during interaction of oil palm .with the mutualistic fungus Glomus etunicatum. A Khodavandi, F Alizadeh – Acta physiologiae plantarum, 2015 –

4.Cyclophilin A as a downstream effector of PI3K/Akt signalling pathway in multiple myeloma cells. ZL Lin, HJ Wu, JA Chen, KC Lin,JH Hsu- Cell biochemistry and funtion, 2015

5.Knock-out of glucose dehydrogenase gene in Gluconacetobacter xylinus for bacterial cellulose production enhancement. CH Kuo, HY Teng, CK Lee – Biotechnology and Bioprocess Engineering, 2015

6.Transcription factor Snail regulates tumor necrosis factor α–mediated synovial fibroblast activation in the rheumatoid joint. SY Chen, AL Shiau, YT Li, CC Lin, IM Jou,MF Liu,CL Wu,CL Wang- Arthritis & Rheumatology, MGMT promoter methylation in non-neoplastic brain. CY Hsu, HL Ho, YC Chang-Chien, YW Chang,CDMing,THo, – Journal of neuro-oncology,2015

7.Seasonal distribution of potentially pathogenic Acanthamoeba species from drinking water reservoirs in Taiwan. PM Kao, BM Hsu, TK Hsu, JH Liu, HY Chang,WT Ji,KJ Tenug,SH Huang,YL Huang- Science and Pollution Research, 2015

8.Prevalence, quantification, and typing of human adenoviruses detected in river water in Taiwan. ZM Huang, BM Hsu, PM Kao, TY Chang,YC Yang,YL Huang – Science and Pollution Research, 2015 – Springer

9.Isolation and Characterization of EgGST, a GlutathioneS-transferase Protein Transcript in Oil Palm. C Toh, P Namasivayam, HC Ling- TROPICAL AGRICULTURAL SCIENCE, Pertanika J. 2015

10.Sugarcane bagasse as nutrient and support material for Cr (VI)-reducing biofilm. WHW Ahmad, JB Chyan, ZA Zakaria…,WA Ahmad- International Biodeterioration & Biodegradation, 2015

11.Stop and smell the pollen: The role of olfaction and vision of the oriental honey buzzard in identifying food. SY Yang, BA Walther, GJ Weng – PloS one, 2015

12.Tumor-specific suicide gene therapy for hepatocellular carcinoma by transcriptionally targeted retroviral replicating vectors. YH Lai, CC Lin, SH Chen, CK Tai – Gene therapy, 2015

13.Molecular cloning and functional characterization of the hepcidin gene from the convict cichlid (Amatitlania nigrofasciata) and its expression pattern in response to lipopolysaccharide challenge. R Chi, LS Liao, RG Wang, CS Jhu, JL Wu-Fish Physiology and Biochemistry,2015

14.Characterization of four B-chromosome-specific RAPDs and the development of SCAR markers on the maize B-chromosome. KW Kao, CY Lin, SF Peng, YM Cheng – Molecular Genetics and Genomics, 2015

15.Evolutionary dynamics of two satellite DNA families in rock lizards of the genus Iberolacerta (Squamata, Lacertidae): different histories but common traits. V Rojo, A Martínez-Lage, M Giovannotti-Chromosome Research,2015

16.TG-interacting factor transcriptionally induced by AKT/FOXO3A is a negative regulator that antagonizes arsenic trioxide-induced cancer cell apoptosis. ZM Liu, HY Tseng, YL Cheng, BW Yeh, WJ Wu,HS Huang- Toxicology and applied Pharmacology, 2015

17.Bacillus formosensis sp. nov., isolated from pesticide wastewater. SY Lin, A Hameed, YC Liu, YH Hsu,WA Lai,WS Yen- CC Young- Microbiology Society, 2015


1.Functional characterization and transcriptional analysis of galE gene encoding a UDP-galactose 4-epimerase in Xanthomonas campestris pv. Campestris. CT Li, CT Liao, SC Du, YP Hsiao, HH Lo,YMHsiao – Microbiological Research, 2014

2.Use of Aspergillus niger β-glucosidase II gene (bglII) promoter elements to construct an efficient expression vector. CH Li, TR Yan – Journal of the Taiwan Institute of Chemical Engineers, 2014

3.Utility of fluorescence in situ hybridization for ploidy and p57 immunostaining in discriminating hydatidiform moles. KH Chen, SC Hsu, HY Chen, KF Ng,TC Cheng – Biochemical and Biophysical Research Communications,2014

4.Expression of a gene encoding β‐ureidopropionase is critical for pollen germination in tomatoes. YH Shen, YH Chen, HY Liu, FY Chiang, Yi-Chieh Wang,Liang-Yu Hou,Jeng-Shane Lin,C-C Lin,Hsin-Hung Lin,Hsi-Mei Lai,Shih-Tong Jeng- Physiologia plantarum, 2014

5.Rubisco expression in the dinoflagellate Symbiodinium sp. is influenced by both photoperiod and endosymbiotic lifestyle. AB Mayfield, YY Hsiao, HK Chen, CS Chen – Marine biotechnology, 2014

6.A mathematical model of bimodal epigenetic control of miR-193a in ovarian cancer stem cells. FHC Cheng, BD Aguda, JC Tsai, M Kochańczyk – PloS one, 2014

7.Anderson B. Mayfield, Yi-Yuong Hsiao. HK Chen, CS Chen – Mar Biotechnol, 2014

8.Organ-and stress-specific expression of the ASR genes in rice. J Pérez-Díaz, TM Wu, R Pérez-Díaz, S Ruíz-Lara – Plant cell reports, 2014

9.Screening differentially expressed genes in an amphipod (Hyalella azteca) exposed to fungicide vinclozolin by suppression subtractive hybridization. YH Wu, TM Wu, CY Hong, YS Wang,JH Yuang – Journal of Environmental Science and Health, 2014

10.Isolation and expression analysis of transcripts encoding metallothioneins in oil palm. AB Al-Shanfari, SNA Abdullah – Biologia plantarum, 2014

11.Detection of torque teno sus virus 1 and 2 in porcine tissues by in situ hybridization using multi-strained pooled probes. Y Lee, CM Lin, CR Jeng, VF Pang – Veterinary microbiology, 2014

12.Optimization protein productivity of human interleukin-2 through codon usage, gene copy number and intracellular tRNA concentration in CHO cells. KC Ou, CY Wang, KT Liu, YL Chen, YC Chen,MDLai,MD Yen- Biochemical and Biophysical Research Communications, 2014

13.Promoter hypermethylation and silencing of tissue factor pathway inhibitor-2 in oral squamous cell carcinoma. YH Lai, RY He, JL Chou Michael W-Y Chan, Yu-Fen Li,Chien-Kuo Tai,- Journal of Translational Medicine , 2014

14.Aberrant DNA methylation in the IFITM1 promoter enhances the metastatic phenotype in an intraperitoneal xenograft model of human ovarian cancer. NH Kim, HY Sung, EN Choi, D Lyu – Oncology reports, 2014

15.Aberrant hypomethylation-mediated AGR2 overexpression induces an aggressive phenotype in ovarian cancer cells. HY Sung, EN Choi, D Lyu, AK Park, Woong Ju Jung-Hyuck Ahn- Oncology reports, 2014

16.Characterization of the Cryptic AV3 Promoter of Ageratum Yellow Vein Virus in Prokaryotic and Eukaryotic Systems. WC Wang, CY Wu, YC Lai, NS Lin, YH Hsu, CC Hu – PloS one, 2014

17.FKBP12 regulates the localization and processing of amyloid precursor protein in human cell lines. FL Liu, TY Liu, FL Kung – Journal of biosciences, 2014

18.Overexpression of mucin 13 due to promoter methylation promotes aggressive behavior in ovarian cancer cells. HY Sung, AK Park, W Ju, JH Ahn – Yonsei medical journal, 2014

19.DNA hypomethylation-mediated overexpression of carbonic anhydrase 9 induces an aggressive phenotype in ovarian cancer cells. HY Sung, W Ju, JH Ahn – Yonsei medical journal, 2014

20.The Chaperone‐like Activity and Structure of Mutant H119G of Rat Lens αB‐crystallin: A Study of Divalent Metal Ion Binding Site. SY Lu, K Reddy, D Naveen Kumar Reddy,Fu-Yung Huang – Journal of the Chinese chemistry society ,2014

21.Amyloid beta-mediated epigenetic alteration of insulin-like growth factor binding protein 3 controls cell survival in Alzheimer’s disease. HY Sung, EN Choi, D Lyu, I Mook-Jung, JH Ahn – PloS one, 2014

22.Zebrafish WNK lysine deficient protein kinase 1 (wnk1) affects angiogenesis associated with VEGF signaling. JG Lai, SM Tsai, HC Tu, WC Chen, FJ Kou, JW Lu – PloS one, 2014

23.Selection of reliable reference genes for gene expression studies using quantitative real-time PCR in navel orange fruit development and pummelo floral organs. J Wu, S Su, L Fu, Y Zhang, L Chai, H Yi – Scientia Horticulturae, 2014

24.The origin of the bifurcated axial skeletal system in the twin-tail goldfish. G Abe, SH Lee, M Chang, SC Liu, HY Tsai,KG Ota,- Nature communication,2014

25.Interference of Co-Amplified Nuclear Mitochondrial DNA Sequences on the Determination of Human mtDNA. HC Yen, SL Li, WC Hsu, P Tang – Plos one, 2014


  1. FimK regulation on the expression of type 1 fimbriae in Klebsiella pneumoniae CG43S3. ZC Wang, CJ Huang, YJ Huang, CC WuHLPeng- Microbiology, 2013

2.Up-regulation of neutrophil activating protein in Helicobacter pylori under high-salt stress: Structural and phylogenetic comparison with bacterial iron-binding ferritins. JH Liao, YH Sun, CH Hsu, YC Lin, SH Wu, CJ Kuo,CHHuang,SHChiou – Biochimie, 2013

3.The role of Sp1 and EZH2 in the regulation of LMX1A in cervical cancer cell. WC Lin, MD Yan, PN Yu, HJ Li, CC Kuo, CL HsuYW Lin- Biochimica et Biophysica Acta (BBA) – Molecular Cell Research,2013

4.The phylogenetic analysis and putative function of lysine 2, 3-aminomutase from methanoarchaea infers the potential biocatalysts for the synthesis of β-lysine. CC Hung, MC Lai – Journal of Microbiology, Immunology and Infection, 2013

5.A transducer for microbial sensory rhodopsin that adopts GTG as a start codon is identified in Haloarcula marismortui. HY Fu, YH Lu, HP Yi, CS Yang – Journal of Photochemistry and Photobiology B: Biology6,2013

6.Effects of Divalent Metal Ions on the Chaperone Activity and Structure of Rat Lens H18G Mutant αB‐Crystallin. SY Lu, FY Huang – Journal of the Chinese Chemical Society, 2013

7.GsmR, a response regulator with an HD‐related output domain in Xanthomonas campestris, is positively controlled by Clp and is involved in the expression of …. YF Liu, CT Liao, WL Song, PC Hsu, SC Du,HHLio,YM Hsiao – The FEBS , 2013

8.ADAR2-mediated editing of miR-214 and miR-122 precursor and antisense RNA transcripts in liver cancers. WH Liu, CH Chen, KH Yeh, CL Li, YJ Wu, DS Chen, Pei-Jer Chen, Shiou-Hwei Yeh- PloS one, 2013

9.Molecular epidemiology of integron-associated antimicrobial gene cassettes in the clinical isolates of Acinetobacter baumannii from northern Taiwan. MF Lin, ML Liou, CC Tu, HW Yeh, Chung-Yu Lan- Annals of laboratory Medicine, 2013

10.The effect of thermal contact resistance on heat management in a shuttling PCR system. JJ Chen, WH Chen, YS Shie – Applied Mechanics and Materials, 2013

11.Sequence analysis and gene expression of putative oil palm chitinase and chitinase-like proteins in response to colonization of Ganoderma boninense and Trichoderma harzianum. KA Yeoh, A Othman, S Meon, F Abdullah… – Molecular biology reports, 2013

12.Screening of Infectious Hypodermal and Haematopoietic Necrosis Virus (IHHNV) infections in wild freshwater prawn, Macrobrachium Rosenbergii, in Malaysia. M Khalid, H Nita –Tropical biomedicine ,2013

13.Polymerase Chain Reaction Microfluidic Devices with Integrated Water Cooling Channel. JJ Chen, CM Shen, SJ Chen – Applied Mechanics and Materials, 2013

14.Real-time PCR method for the detection and quantification of Acanthamoeba species in various types of water samples. PM Kao, MC Tung, BM Hsu, HL Tsai, CY She, Shu-Min ShenWen-Chien Huang- Parasitology research, 2013

15.A simple and effective method for RNA isolation and cDNA library construction from the brown seaweed Sargassum polycystum (Fucales, Phaeophyceae). MC Sim, CL Ho, SM Phang – Journal of applied phycology, 2013

16.Epigenetic silencing of PTPRR activates MAPK signaling, promotes metastasis and serves as a biomarker of invasive cervical cancer. PH Su, YW Lin, RL Huang, YP Liao, HY Lee- Oncogene,2013

17.A Microfluidic Device Integrated Active Cooling Channel for DNA Amplification. JJ Chen, XC Qiu, CM Shen, SJ Chen, Yu Wei Ko – Transactions of the Canadian Society for Mechanical Engineering, 2013

18.Analytical study of a microfludic DNA amplification chip using water cooling effect. JJ Chen, CM Shen, YW Ko – Biomedical microdevices, 2013

19.Differential regulation and activity against oxidative stress of Dps proteins in Bacillus cereus. JC Shu, PC Soo, JC Chen, SH Hsu, LC Chen,CYChen,SHLiang,LMBuu,CCCen – International Journal of Medical Microbiology, 2013

20.Continuous-Flow Polymerase Chain Reaction Chip by Water Cooling. JJ Chen, SJ Chen, YW Ko – Engineering in Agriculture, Environment and Food, 2013

21.Estrogen receptor α (ESR1) over-expression mediated apoptosis in Hep3B cells by binding with SP1 proteins. Chuan-Chou Tu, V Bharath Kumar, Cecilia Hsuan Day, Wei-Wen Kuo, Su-Peng Yeh, Ray-Jade Chen, Chen-Rong Liao, Hsiao-Yu Chen, Fuu-Jen Tsai, Wen-Jun Wu, Chih-Yang Huang- Journal of molecular endocrinology, 2013

22.Comparison of viremia of type II porcine reproductive and respiratory syndrome virus in naturally infected pigs by zip nucleic acid probe-based real-time PCR. CN Lin, WH Lin, LN Hung,SYWang,MT Chiou – BMC veterinary central, 2013